Abstract Background Sepsis, a life-threatening organ dysfunction caused by a dysregulated systemic immune response to infection, associates with reduced responsiveness to subsequent infections.How such tolerance is acquired is not well understood but is known to involve epigenetic and transcriptional dysregulation.Methods Bead arrays were used to c
Silica nanoparticles have become promising carriers for drug delivery or gene therapy.Endothelial cells could be directly exposed to silica nanoparticles by intravenous administration.However, the underlying toxic effect mechanisms of silica nanoparticles on endothelial cells are still poorly understood.In order to clarify the cytotoxicity of endot
In the recent history of the MUSHROOM SYNERGY Brazilian Territorial Politics, we can observe the option for the elaboration and implementation of Politics for Territorial Arrangement, in a national level, which contemplates the contemporary management methodologies.This means, the decentralization and consequent social participation as also the art
Objective: to validate a model of the reduced version of the Brazilian Scale of Moral Distress in Nurses.Method: methodological study, with a sample of 269 nurses from a public university hospital in southern Brazil.A sociodemographic questionnaire and the Brazilian Moral Distress Scale for Nurses were used.Descriptive statistics, structural equati